Treatment of adynamic bone disease in a haemodialysis patient with teriparatide

نویسندگان

  • Panagiotis Giamalis
  • Dominiki Economidou
  • Chrysostomos Dimitriadis
  • Dimitrios Memmos
  • Aikaterini Papagianni
  • Georgios Efstratiadis
چکیده

Prevalence of adynamic bone disease (ABD), characterized by low bone turnover and absence or a reduced number of osteoblasts and osteoclasts, is increasing steadily over the last years. We present a dialysis patient, with recurrent bone fractures and biopsy-proven ABD, who was treated with teriparatide. Nine months after initiation of treatment, iPTH plasma levels increased to 520 pg/mL and a second bone biopsy revealed high bone turnover, normal mineralization and normal bone volume. Two years later, iPTH was 250-350 pg/dL and bone metabolism parameters within normal range. The probable utility of teriparatide in the treatment of ABD in dialysis patients is discussed.

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عنوان ژورنال:

دوره 8  شماره 

صفحات  -

تاریخ انتشار 2015